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“The American Age of Inflation is finished.” So says economist Robert Samuelson in his December 2nd Washington Post column.

This type of refrain is common. We often hear that this or that is ended – that such things only happen in the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

past, and that our new, more advanced time is above such mundane things. It is reminiscent of the late ‘90’s declarations of the end of value investing, and the meaninglessness of p/e ratios, and the (can you believe it?) end of bear m

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

rkets. Such drivel is what houses of cards are built on.

It is, in fact, just such declarations that should alert us to the impending disaster that awaits. The easiest way to know when a trend or characteristic may be on the horizon i

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s the cacophony of pundits extolling its end. When the columnists and advisors in the late ‘90’s told us that it was a “new era”, and that we needn’t worry about overpriced stocks, that was precisely the time to worry.

Today, when we h

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ar economists like Samuelson announcing the “end” of inflation, it is again time to worry. We already sensed the alignment of a variety of factors that could lead toward the re-emergence of inflation, but the fact that apologists for go

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

vernment policy (economists) see the need to talk it away only serves as confirmation that the time is at hand. Inflation is apparently not only on the way, it is probably at our doorstep. The massive spending spree and resulting dollar

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

devaluation should lead us to that conclusion anyway. We’ve been expecting some level of inflation for some time. But, when we start hearing such defensive postures from those who don’t want to hear the truth, well, its time to begin p

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

lanning for it more seriously.

In Samuelson’s defense, his article focuses mostly on the idea that markets have risen rapidly over the past 20 years (since Reagan reduced inflation in 1982) due to the benefit of lower inflation. He arg

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

es that we will no longer benefit from that improvement. But his error is in thinking that things will now be “flat”, and that inflation was a one-time event that will not be revisited.

He displays a lack of political understanding. As

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

long as politicians can benefit from printing and spending other people’s money, we’ll see more inflation. Of course, the fact that we anticipate inflation in the financial system does not mean that this will affect all goods equally.

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Certainly, our enhanced trade relations have caused prices of some imported goods to drop significantly. However, as the dollar drops in value, our ability to buy imports cheaply will also be reduced, and already, prices of imported goo

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

s are rising from their lows. Since these cheap imports have been masking inflation for some time, this eventuality will speed the negative impact. Oil prices are a prime example of this phenomenon. This kind of price increase is natura

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

lly uncomfortable, but is a natural result of the free-floating currency regime we follow, and it is actually part of a healthy mechanism for refocusing our efforts. It isn’t the price increases that should surprise us, and they themsel

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

es are not the problem. This is simply the result of a dollar that is plummeting in value. We need to realize that it is not the producers of goods that are doing us harm, but the governments who run our currency into the ground. Eventu

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ally, we may expect to see prices rising on most goods, including both those produced locally, as well as imports.

The result is important for investors. Rising price levels will mean your savings are worth less, and your retirement ac

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ounts must grow just to hold their value. It has been many years since this nation has dealt with high inflation, and most of us have forgotten how to deal with it. Since Reagan, Volcker, and Greenspan worked to defeat the wild inflatio

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

n of the Carter, Ford, and Nixon years, we haven’t had to deal with this devastating bugaboo, but today we should plan for it.

In addition to damaging our savings, inflation can make our debts less bothersome. High inflation will push

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nterest rates higher, however, so only borrowers with fixed rates will benefit. Others will probably experience rising interest rates on their credit cards and struggle to pay them off. Never before in U.S. history have so many carrie

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

d so much credit card debt in a period of high inflation. One might expect higher default levels. Inflation will also boost home prices without increasing value, and uplift profit levels without growing real assets. The outcome will be

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

igher taxes and tougher competition. In the end, it will be a worse time for bonds, and while stocks will be a better place to be, high-flying growth companies will often disappoint. It is a wonderful time to think like a value investor

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Stainless steel fasteners are made of steel that has been mixed with at least a ten percent compound of chromium, and possibly other metals, so that the steel doesn’t rust or corrode. This makes stainless steel fasteners great for outdoor conditions, where there is a lot of water or moisture.

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