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Investors today are flooded with various choices of investment instruments like fixed deposits, shares, unit trust, gold, bonds, etc. Before investing, it's

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

important to gauge your risk appetite.

Risk appetite is sometimes influenced by our culture, upbringing, character, age or profession. For instance, the old

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

r a person gets the more risk averse he's likely to be. Therefore, there are factors to consider when making an investment. Ask yourself; how much capital d

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

I have to invest? What is my expected rate of return? Is it short, medium or long term investment? What are the options available to me? How much I could

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

afford to lose? How do these options compare against each other? Have I considered all possible costs of investment?

By answering these questions, we can n

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

rrow down the choices to those that most suit us. This is one method of profiling. It reduces confusion in deciding which type of investments we should inve

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

st in.

The famous saying, 'diversify your investment portfolio'; in property investment, diversification can come in the form of various property types, such

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

as residential, commercial and industrial. In shares, it would be investing in different companies involved in different industries. If one share suffers lo

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ses, your overall investment is set off by investments in other companies that may still be profitable.

There are basically three broad streams of growth for

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

property investments, which are capital growth (buy and hold), rental income (cash flow) and a combination of both. Some investors look for high yield proper

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ies (for the rental income) while others go for capital growth or appreciation. The best would be a combination of both.

Prior investing, bear in mind the i

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ncidental costs involved like legal fees, stamp duty, assessment, quit rent, management fees, insurance, valuation fees and so on. There're many methods for

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nvestment appraisal and one of the most commonly used, called Yield.

For instance, an existing three-storey shop office is currently tenanted at a net income

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

of $5,000 per month and the property is going for $1 million. Is this a good investment?

Yield = ($5,000 x 12) ? $1million = 6%

Assuming, current fixed dep

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

sit rates are at 4% per annum, thus, this investment gives you a 2% higher rate of return than placing your money in the bank. The yield should be more than

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

urplus the cost of funds. Seasoned investors would go for a property investment with a yield of twice the fixed deposit rates, which in this case - 8% or mor

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e. There are two ways this can be achieved; either increase the rentals or reduce the purchase price. For instance, the rental will be revised at the next r

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nt review in a month to $6,000 per month for a further two year term and the seller is willing to consider a price of $900,000. Now your yield hits 8%.

Inve

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

tment is sometimes very complex thus in order to succeed you requires lots of knowledge and experience. Read extensively, get the facts and don't be afraid o

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

shy seeking for professional help before making any decisions.

Always prepare at least three to six months of your monthly living expenses in saving account

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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