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I want you to take a good long look at your debt. Do you really know what it costs you to be in debt? Are you thinking that you can handle it or is it getting you down?

Once you start really analyzing your debt p

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

osition and the cost (to yourself) of having the debt, the results can be mind-numbingly shocking.

I’ve found that debt is a lot like smoking. When you start out, you believe you’re in control and you can quit at

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

any time. As the months and the years roll past, this initial belief does not fade away. With every debt you incur, the mantra “I can afford this”, repeats itself in your subconscious until you wake up one morning

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

and realize that you’re in over your head.

Debt has well and truly caught you in its trap. Debt has become a bad habit.

And just like any bad habit, debt requires as much hard work and discipline to shake. The f

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

irst step in the process is to acknowledge that you have a problem - instead of turning a blind eye, hoping it will go away or thinking that you’ll get around to it some day in the future.

One of the motivators to

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

setting your feet on the path to debt free living is to look at the real cost of that debt. What is it doing to you? Where does it hurt the most?

Most debts (the ones that make you cry into your morning coffee an

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

yway) are the ones that are incurred for a period exceeding one year. You’ve probably seen or heard advertisements that go something like this:

Buy your ‘Wiggly Snoogle’ for this special one time limited offer tod

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ay – 24 easy monthly instalments.

Beware – this is where you can fall into the deadliest trap of them all. The interest rates are usually above average and you’re stuck into a long term contract. Yes, getting you

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

r Wiggly Snoogle with the 25 000 features sounds like a good idea because of the easy monthly payments; especially if you compare it to the one time lump sum payment. (By the way, using the ‘lump sum’ to ‘monthly

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

payment’ comparison is a well known sales technique to separate you from your hard earned cash.)

Let’s take this out of the realm of philosophy with a real world example:

You borrow $ 10,000 to buy a new car. Ove

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

r a 48 month period – that’s 4 years of monthly payments – you will be paying an additional $ 2,000 in interest. So, your $ 10,000 vehicle is actually costing you $ 12,000. The cost of that debt is a whopping $ 2,

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

000. If you had taken that $ 2,000 and invested it over the same period, it could have grown to $ 3,000. Instead, it has disappeared into someone else’s pocket – never to be seen again.

This is where the lenders

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

make their money. The longer they can have you in their clutches, the longer they can smile all the way to the bank and you groaning on the way to work.

Now I’m not saying that you shouldn’t have a car – it’s just

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

an example of the REAL cost of debt. Sometimes debt is unavoidable, but as a species we’ve become too complacent about debt and we jump into it without thinking.

Your Magic Plastic (a.k.a. Credit Card) is another

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

one of those fiendishly sneaky evils the banks developed to rid you of your money. If – and that’s a big if – you manage your credit card correctly and pay off the full amount at the end of each month, they can be

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

great to have and smooth the little rough patches in life. But most of us only pay the minimum amount required each month – and that’s exactly what the banks want. It leaves you in the red and owing them money.

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

Which gives them ample opportunity to apply the thumb screws. Remember, every month you’re in the red, you’re paying interest on the outstanding amount which gets added to your bill.

The big mistake we all make is

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

to look at our monthly statement and say: “Hey, that’s not too bad. I can still afford my repayments. And I have some credit available to buy that wiggly snoogle as well!” The problem arises when you battle to m

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ake your income stretch through the month because of the various different repayments you have to make.

It’s critically important that you start looking at the TOTAL COST of your debt over your lifetime. Once you’

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

re over the shock and horror of how much of your hard earned cash is going up in smoke, you’ll be in a position to tackle the problem head on and take the path to debt free living.

Remeber: Bad debt is a bad habit.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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How can a medical practice survive with slow revenue? too many claims denial and rejection? Empirically, insurance companies will delay or deny claims payments! The solution here is to get the collection done as effectively as it can.

Mary, an executive vice president of a large company, was frustrated. She had big plans for her division, but when she handed a project off to one of her managers, it would end up either completed late, or not completed at all. She was ready to fire the entire group and start over!

The most important part of the web site concept is the domain name. Get it wrong and your site may never show its full potential. What makes a good domain name you ask?

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